抖阴短视频

What did we do?

• We 鈥榬ecruited鈥� participants to the trial and obtained their informed consent.
• We measured participants鈥� mood before and after eating a piece of chocolate using a 0-10 sliding scale.
• We 鈥�randomised鈥� participants to either the control group (鈥榩lain鈥� chocolate) or the intervention (鈥榝lavoured鈥� chocolate).
• To make the study a fair comparison, participants did not know whether they were given plain or flavoured chocolate (this is known as 鈥�blinding鈥�). We asked participants to guess which chocolate they had eaten.
• After completing The Chocolate Trial, we asked whether participants understanding of clinical trials had changed.
• Data were captured using PenCTU鈥檚 instance of REDCap Cloud (a clinical trial electronic data capture system), and exported directly in to the statistical software package "R" in real time, for the purposes of live reporting, visualisation and analysis.
  

Who took part?

• 51 participants took part in the trial over the two one-hour sessions (25 allocated to plain chocolate and 26 allocated to flavoured chocolate).
• Just over half of the participants were University staff.
• Nearly two thirds were female.
• There was a wide range of age amongst the participants.

Does flavoured chocolate improve mood more than plain chocolate?

• Participant鈥檚 mean mood before chocolate (baseline) was 6.5 and after chocolate (follow-up) was 7.4 points. Figure 1 summarises participants鈥� change in mood between baseline and follow-up.
• The mean change in mood after eating chocolate was 1.2 points for the plain chocolate and 0.6 points for the flavoured chocolate.
• Plain chocolate improved participant鈥檚 mood by around 0.6 points more than the flavoured chocolate.
• The 95% confidence interval for the difference in change in mood was -0.1 to 1.2 points.
• This shows that whilst there is some suggestion that plain chocolate is better than flavoured chocolate at improving mood, the difference is not statistically significant.

Could participants guess correctly their allocated chocolate?

Whilst the two chocolates looked very similar, most participants were able to correctly identify which chocolate they had eaten:

• 81% of participants who ate the flavoured chocolate guessed correctly.
• 96% of participants who ate the plain chocolate guessed correctly.

One participant who ate the plain (control) chocolate guessed incorrectly; this demonstrates the 鈥�placebo effect鈥�, where a participant鈥檚 expectation of the treatment (chocolate) may affect their perceived experience.

Did the Chocolate Trial increase understanding of clinical trials?

• 86% of participants provided feedback on whether their understanding of clinical trials had increased.
• 73% of participants providing feedback said that their understanding of clinical trials had increased; almost half (43%) reported that their understanding increased a lot (Figure 2).

What did participants think about the event?

Participant鈥檚 feedback was overwhelmingly positive (Figure 3)

• 鈥淎 great overview of a clinical trial.鈥�
• 鈥淕reat friendly staff. Great to see a trial in action.鈥�
• 鈥淕reat way to improve people鈥檚 understanding at what鈥檚 involved in clinical trials.鈥�
• 鈥淕ood fun practical way to introduce people to the concept of clinical trials.鈥�